Computational biology of cancer : lecture notes and mathematical modeling /
The book shows how mathematical and computational models can be used to study cancer biology. It introduces the concept of mathematical modeling and then applies it to a variety of topics in cancer biology. These include aspects of cancer initiation and progression, such as the somatic evolution of...
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| Format: | Electronic eBook |
| Language: | English |
| Published: |
Hackensack, NJ :
World Scientific,
2005.
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| Subjects: | |
| Online Access: |
Full text (MFA users only) |
| ISBN: | 9812701362 9789812701367 9789812560278 9812560270 1281897086 9781281897084 |
| Local Note: | ProQuest Ebook Central |
Table of Contents:
- Preface; Contents; Chapter 1 Cancer and somatic evolution; Chapter 2 Mathematical modeling of tumorigenesis; Chapter 3 Cancer initiation: one-hit and two-hit stochastic models; Chapter 4 Microsatellite and chromosomal instability in sporadic and familial cancers; Chapter 5 Cellular origins of cancer; Chapter 6 Costs and benefits of chromosomal instability; Chapter 7 DNA damage and genetic instability; Chapter 8 Tissue aging and the development of cancer; Chapter 9 Basic models of tumor inhibition and promotion; Chapter 10 Mechanisms of tumor neovascularization.